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Nicotinamide Promotes Formation of Retinal Organoids From Human Pluripotent Stem Cells via Enhanced Neural Cell Fate Commitment
Retinal organoids (ROs) derived from human pluripotent stem cells (hPSCs) recapitulate key features of retinogenesis and provide a promising platform to study retinal development and disease in a human context. Although multiple protocols are currently in use, hPSCs exhibit tremendous variability in...
Autores principales: | Regent, Florian, Batz, Zachary, Kelley, Ryan A., Gieser, Linn, Swaroop, Anand, Chen, Holly Y., Li, Tiansen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9247291/ https://www.ncbi.nlm.nih.gov/pubmed/35783089 http://dx.doi.org/10.3389/fncel.2022.878351 |
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