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Impact of Metformin Treatment on Human Placental Energy Production and Oxidative Stress

Metformin is increasingly prescribed in pregnancy, with beneficial maternal effects. However, it is not known how metformin-treatment impacts metabolism and energy production in the developing feto-placental unit. We assessed the human placental response to metformin using both in vivo and in vitro...

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Detalles Bibliográficos
Autores principales: Tarry-Adkins, Jane L., Robinson, India G., Reynolds, Rebecca M., Aye, Irving L. M. H., Charnock-Jones, D. Stephen, Jenkins, Benjamin, Koulmann, Albert, Ozanne, Susan E., Aiken, Catherine E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9247405/
https://www.ncbi.nlm.nih.gov/pubmed/35784487
http://dx.doi.org/10.3389/fcell.2022.935403