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A Non-Canonical Role for IRE1α Links ER and Mitochondria as Key Regulators of Astrocyte Dysfunction: Implications in Methamphetamine use and HIV-Associated Neurocognitive Disorders

Astrocytes are one of the most numerous glial cells in the central nervous system (CNS) and provide essential support to neurons to ensure CNS health and function. During a neuropathological challenge, such as during human immunodeficiency virus (HIV)-1 infection or (METH)amphetamine exposure, astro...

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Detalles Bibliográficos
Autores principales: Proulx, Jessica, Stacy, Satomi, Park, In-Woo, Borgmann, Kathleen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9247407/
https://www.ncbi.nlm.nih.gov/pubmed/35784841
http://dx.doi.org/10.3389/fnins.2022.906651