Competitive Binding of Ozanimod and Other Sphingosine 1-Phosphate Receptor Modulators at Receptor Subtypes 1 and 5

Ozanimod, a sphingosine 1-phosphate (S1P) receptor modulator, binds with high affinity selectively to S1P receptor subtypes 1 (S1P(1)) and 5 (S1P(5)), and is approved in multiple countries for treating adults with relapsing forms of multiple sclerosis (MS) or moderately to severely active ulcerative...

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Detalles Bibliográficos
Autores principales: Selkirk, Julie V., Bortolato, Andrea, Yan, Yingzhuo Grace, Ching, Nathan, Hargreaves, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9247443/
https://www.ncbi.nlm.nih.gov/pubmed/35784713
http://dx.doi.org/10.3389/fphar.2022.892097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9247443/
https://www.ncbi.nlm.nih.gov/pubmed/35784713
http://dx.doi.org/10.3389/fphar.2022.892097

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