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Molecular Dissection of a Conserved Cluster of miRNAs Identifies Critical Structural Determinants That Mediate Differential Processing

Differential processing is a hallmark of clustered microRNAs (miRNAs) and the role of position and order of miRNAs in a cluster together with the contribution of stem-base and terminal loops has not been explored extensively within the context of a polycistronic transcript. To elucidate the structur...

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Detalles Bibliográficos
Autores principales: Pandey, Manish, Luhur, Arthur, Sokol, Nicholas S., Chawla, Geetanjali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9247461/
https://www.ncbi.nlm.nih.gov/pubmed/35784477
http://dx.doi.org/10.3389/fcell.2022.909212