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Inhibitory effects of the atypical antipsychotic, clozapine, on voltage-dependent K(+) channels in rabbit coronary arterial smooth muscle cells

To investigate the adverse effects of clozapine on cardiovascular ion channels, we examined the inhibitory effect of clozapine on voltage-dependent K(+) (Kv) channels in rabbit coronary arterial smooth muscle cells. Clozapine-induced inhibition of Kv channels occurred in a concentration-dependent ma...

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Detalles Bibliográficos
Autores principales: Kang, Minji, Heo, Ryeon, Park, Seojin, Mun, Seo-Yeong, Park, Minju, Han, Eun-Taek, Han, Jin-Hee, Chun, Wanjoo, Ha, Kwon-Soo, Park, Hongzoo, Jung, Won-Kyo, Choi, Il-Whan, Park, Won Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9247706/
https://www.ncbi.nlm.nih.gov/pubmed/35766005
http://dx.doi.org/10.4196/kjpp.2022.26.4.277