Analysis of MRI-derived spleen iron in the UK Biobank identifies genetic variation linked to iron homeostasis and hemolysis

The spleen plays a key role in iron homeostasis. It is the largest filter of the blood and performs iron reuptake from old or damaged erythrocytes. Despite this role, spleen iron concentration has not been measured in a large, population-based cohort. In this study, we quantify spleen iron in 41,764...

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Detalles Bibliográficos
Autores principales: Sorokin, Elena P., Basty, Nicolas, Whitcher, Brandon, Liu, Yi, Bell, Jimmy D., Cohen, Robert L., Cule, Madeleine, Thomas, E. Louise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9247824/
https://www.ncbi.nlm.nih.gov/pubmed/35568031
http://dx.doi.org/10.1016/j.ajhg.2022.04.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9247824/
https://www.ncbi.nlm.nih.gov/pubmed/35568031
http://dx.doi.org/10.1016/j.ajhg.2022.04.013

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