Targeting Inhibition of Accumulation and Function of Myeloid-Derived Suppressor Cells by Artemisinin via PI3K/AKT, mTOR, and MAPK Pathways Enhances Anti-PD-L1 Immunotherapy in Melanoma and Liver Tumors

Despite the remarkable success and efficacy of immune checkpoint blockade (ICB) therapy such as anti-PD-L1 antibody in treating cancers, myeloid-derived suppressor cells (MDSCs) that lead to the formation of the protumor immunosuppressive microenvironment are one of the major contributors to ICB res...

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Detalles Bibliográficos
Autores principales: Zhang, Mengqi, Wang, Lulu, Liu, Wan, Wang, Tian, De Sanctis, Francesco, Zhu, Lifang, Zhang, Guizhong, Cheng, Jian, Cao, Qin, Zhou, Jingying, Tagliabue, Aldo, Bronte, Vincenzo, Yan, Dehong, Wan, Xianchun, Yu, Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9247850/
https://www.ncbi.nlm.nih.gov/pubmed/35785030
http://dx.doi.org/10.1155/2022/2253436

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9247850/
https://www.ncbi.nlm.nih.gov/pubmed/35785030
http://dx.doi.org/10.1155/2022/2253436

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