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In silico analysis of SARS-CoV-2 spike protein N501Y and N501T mutation effects on human ACE2 binding

The SARS-CoV-2 is an RNA-based virus and the most vital step of its survival is the attachment to hACE2 through its spike protein. Although SARS-CoV-2 has the ability to maintain high accurate replication and it can be accepted as a low mutation risked virus, it already showed more than nine thousan...

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Detalles Bibliográficos
Autores principales: Çubuk, Hasan, Özbi̇l, Mehmet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9247859/
https://www.ncbi.nlm.nih.gov/pubmed/35809511
http://dx.doi.org/10.1016/j.jmgm.2022.108260