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Possible neuroprotective effects of amide alkaloids from Bassia indica and Agathophora alopecuroides: in vitro and in silico investigations

In Alzheimer's disease (AD), the accumulation of amyloid-β plaques, overactivity of MAO-B, and phosphorylated tau protein in the central nervous system result in neuroinflammation and cognitive impairments. Therefore, the multi-targeting of these therapeutic targets has emerged as a promising s...

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Detalles Bibliográficos
Autores principales: Othman, Ahmed, Sayed, Ahmed M., Amen, Yhiya, Shimizu, Kuniyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248040/
https://www.ncbi.nlm.nih.gov/pubmed/35873339
http://dx.doi.org/10.1039/d2ra02275c