Aberrant SPOP-CHAF1A ubiquitination axis triggers tumor autophagy that endows a therapeutical vulnerability in diffuse large B cell lymphoma

PURPOSE: Aberrant epigenetic changes, like DNA methylation, histone modifications, or ubiquitination, could trigger metabolic disorders in human cancer cells. This study planed to uncover the biological roles of epigenetic SPOP/CHAF1A axis in modulating tumor autophagy during Diffuse large B-cell ly...

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Detalles Bibliográficos
Autores principales: Yan, Wei, Shi, Xue, Wang, Huihan, Liao, Aijun, Yang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248129/
https://www.ncbi.nlm.nih.gov/pubmed/35773729
http://dx.doi.org/10.1186/s12967-022-03476-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248129/
https://www.ncbi.nlm.nih.gov/pubmed/35773729
http://dx.doi.org/10.1186/s12967-022-03476-7

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