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Aberrant SPOP-CHAF1A ubiquitination axis triggers tumor autophagy that endows a therapeutical vulnerability in diffuse large B cell lymphoma

PURPOSE: Aberrant epigenetic changes, like DNA methylation, histone modifications, or ubiquitination, could trigger metabolic disorders in human cancer cells. This study planed to uncover the biological roles of epigenetic SPOP/CHAF1A axis in modulating tumor autophagy during Diffuse large B-cell ly...

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Detalles Bibliográficos
Autores principales:	Yan, Wei, Shi, Xue, Wang, Huihan, Liao, Aijun, Yang, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248129/ https://www.ncbi.nlm.nih.gov/pubmed/35773729 http://dx.doi.org/10.1186/s12967-022-03476-7

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