Cargando…

A novel CREB5/TOP1MT axis confers cisplatin resistance through inhibiting mitochondrial apoptosis in head and neck squamous cell carcinoma

BACKGROUND: Cisplatin resistance is one of the main causes of treatment failure and death in head and neck squamous cell carcinoma (HNSCC). A more comprehensive understanding of the cisplatin resistance mechanism and the development of effective treatment strategies are urgent. METHODS: RNA sequenci...

Descripción completa

Detalles Bibliográficos
Autores principales: Tong, Tong, Qin, Xing, Jiang, Yingying, Guo, Haiyan, Wang, Xiaoning, Li, Yan, Xie, Fei, Lu, Hao, Zhai, Peisong, Ma, Hailong, Zhang, Jianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248137/
https://www.ncbi.nlm.nih.gov/pubmed/35773668
http://dx.doi.org/10.1186/s12916-022-02409-x