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Single transcription factor efficiently leads human induced pluripotent stem cells to functional microglia

BACKGROUND: Microglia are innate immune cells that are the only residential macrophages in the central nervous system. They play vital physiological roles in the adult brain and during development. Microglia are particularly in the spotlight because many genetic risk factors recently identified for...

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Detalles Bibliográficos
Autores principales: Sonn, Iki, Honda-Ozaki, Fumiko, Yoshimatsu, Sho, Morimoto, Satoru, Watanabe, Hirotaka, Okano, Hideyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248164/
https://www.ncbi.nlm.nih.gov/pubmed/35773727
http://dx.doi.org/10.1186/s41232-022-00201-1