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Single transcription factor efficiently leads human induced pluripotent stem cells to functional microglia
BACKGROUND: Microglia are innate immune cells that are the only residential macrophages in the central nervous system. They play vital physiological roles in the adult brain and during development. Microglia are particularly in the spotlight because many genetic risk factors recently identified for...
Autores principales: | Sonn, Iki, Honda-Ozaki, Fumiko, Yoshimatsu, Sho, Morimoto, Satoru, Watanabe, Hirotaka, Okano, Hideyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248164/ https://www.ncbi.nlm.nih.gov/pubmed/35773727 http://dx.doi.org/10.1186/s41232-022-00201-1 |
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