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Clinical predictors of response to methotrexate in patients with rheumatoid arthritis: a machine learning approach using clinical trial data

BACKGROUND: Methotrexate is the preferred initial disease-modifying antirheumatic drug (DMARD) for rheumatoid arthritis (RA). However, clinically useful tools for individualized prediction of response to methotrexate treatment in patients with RA are lacking. We aimed to identify clinical predictors...

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Detalles Bibliográficos
Autores principales: Duong, Stephanie Q., Crowson, Cynthia S., Athreya, Arjun, Atkinson, Elizabeth J., Davis, John M., Warrington, Kenneth J., Matteson, Eric L., Weinshilboum, Richard, Wang, Liewei, Myasoedova, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248180/
https://www.ncbi.nlm.nih.gov/pubmed/35778714
http://dx.doi.org/10.1186/s13075-022-02851-5