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Clinical predictors of response to methotrexate in patients with rheumatoid arthritis: a machine learning approach using clinical trial data
BACKGROUND: Methotrexate is the preferred initial disease-modifying antirheumatic drug (DMARD) for rheumatoid arthritis (RA). However, clinically useful tools for individualized prediction of response to methotrexate treatment in patients with RA are lacking. We aimed to identify clinical predictors...
Autores principales: | Duong, Stephanie Q., Crowson, Cynthia S., Athreya, Arjun, Atkinson, Elizabeth J., Davis, John M., Warrington, Kenneth J., Matteson, Eric L., Weinshilboum, Richard, Wang, Liewei, Myasoedova, Elena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248180/ https://www.ncbi.nlm.nih.gov/pubmed/35778714 http://dx.doi.org/10.1186/s13075-022-02851-5 |
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