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Loss of tau expression attenuates neurodegeneration associated with α-synucleinopathy

BACKGROUND: Neuronal dysfunction and degeneration linked to α-synuclein (αS) pathology is thought to be responsible for the progressive nature of Parkinson’s disease and related dementia with Lewy bodies. Studies have indicated bidirectional pathological relationships between αS pathology and tau ab...

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Detalles Bibliográficos
Autores principales: Vermilyea, Scott C., Christensen, Anne, Meints, Joyce, Singh, Balvindar, Martell-Martínez, Héctor, Karim, Md. Razaul, Lee, Michael K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248195/
https://www.ncbi.nlm.nih.gov/pubmed/35773715
http://dx.doi.org/10.1186/s40035-022-00309-x