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Coexistence of two missense mutations in the KRAS gene in adenocarcinoma of the lung: a possible indicator of poor prognosis

BACKGROUND: KRAS mutations are present in up to 30% of patients with lung adenocarcinoma. The two most common KRAS mutations in non-small cell lung cancer (NSCLC) are G12C (~40%) and G12V (~22%). We describe the case of a 63-year-old Asian male patient with a very aggressive lung adenocarcinoma harb...

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Detalles Bibliográficos
Autores principales: Spinelli, Manuela, Du Parcq, Persephone, Gupta, Nandita, Khorashad, Jamshid, Viola, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pacini Editore srl 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248237/
https://www.ncbi.nlm.nih.gov/pubmed/35775708
http://dx.doi.org/10.32074/1591-951X-334