Time-resolved proximity labeling of protein networks associated with ligand-activated EGFR

Ligand binding to the EGF receptor (EGFR) triggers multiple signal-transduction processes and promotes endocytosis of the receptor. The mechanisms of EGFR endocytosis and its cross-talk with signaling are poorly understood. Here, we combine peroxidase-catalyzed proximity labeling, isobaric peptide t...

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Detalles Bibliográficos
Autores principales: Verdaguer, Mireia Perez, Zhang, Tian, Surve, Sachin, Paulo, Joao A., Wallace, Callen, Watkins, Simon C., Gygi, Steven P., Sorkin, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248364/
https://www.ncbi.nlm.nih.gov/pubmed/35705039
http://dx.doi.org/10.1016/j.celrep.2022.110950

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248364/
https://www.ncbi.nlm.nih.gov/pubmed/35705039
http://dx.doi.org/10.1016/j.celrep.2022.110950

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