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Time-resolved proximity labeling of protein networks associated with ligand-activated EGFR
Ligand binding to the EGF receptor (EGFR) triggers multiple signal-transduction processes and promotes endocytosis of the receptor. The mechanisms of EGFR endocytosis and its cross-talk with signaling are poorly understood. Here, we combine peroxidase-catalyzed proximity labeling, isobaric peptide t...
Autores principales: | Verdaguer, Mireia Perez, Zhang, Tian, Surve, Sachin, Paulo, Joao A., Wallace, Callen, Watkins, Simon C., Gygi, Steven P., Sorkin, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248364/ https://www.ncbi.nlm.nih.gov/pubmed/35705039 http://dx.doi.org/10.1016/j.celrep.2022.110950 |
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