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Anemia Increases Oxygen Extraction Fraction in Deep Brain Structures but Not in the Cerebral Cortex

Sickle cell disease (SCD) is caused by a single amino acid mutation in hemoglobin, causing chronic anemia and neurovascular complications. However, the effects of chronic anemia on oxygen extraction fraction (OEF), especially in deep brain structures, are less well understood. Conflicting OEF values...

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Detalles Bibliográficos
Autores principales: Shen, Jian, Miao, Xin, Vu, Chau, Xu, Botian, González-Zacarías, Clio, Nederveen, Aart J., Wood, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248375/
https://www.ncbi.nlm.nih.gov/pubmed/35784894
http://dx.doi.org/10.3389/fphys.2022.896006