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The Human Milk Oligosaccharide 2′-Fucosyllactose Alleviates Liver Steatosis, ER Stress and Insulin Resistance by Reducing Hepatic Diacylglycerols and Improved Gut Permeability in Obese Ldlr-/-.Leiden Mice

Non-alcoholic fatty liver disease (NAFLD) is a complex multifactorial disorder that is associated with gut dysbiosis, enhanced gut permeability, adiposity and insulin resistance. Prebiotics such as human milk oligosaccharide 2′-fucosyllactose are thought to primarily improve gut health and it is unc...

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Detalles Bibliográficos
Autores principales: Gart, Eveline, Salic, Kanita, Morrison, Martine C., Giera, Martin, Attema, Joline, de Ruiter, Christa, Caspers, Martien, Schuren, Frank, Bobeldijk-Pastorova, Ivana, Heer, Marianne, Qin, Yan, Kleemann, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248376/
https://www.ncbi.nlm.nih.gov/pubmed/35782914
http://dx.doi.org/10.3389/fnut.2022.904740