Novel method utilizing bisulfite conversion with dual amplification‐refractory mutation system polymerase chain reaction to detect circulating pancreatic β‐cell cfDNA

AIMS/INTRODUCTION: Several research groups have reported methods for quantifying pancreatic beta cell (β‐cell) injury by measuring β‐cell‐specific CpG unmethylation of the insulin gene in circulation using digital droplet PCR or next‐generation sequencing. However, these methods have certain disadva...

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Detalles Bibliográficos
Autores principales: Okada, Asami, Yamada‐Yamashita, Misuzu, Tominaga, Yukari, Jo, Kyoka, Mori, Hiroyasu, Suzuki, Reiko, Ishizu, Masashi, Tamaki, Motoyuki, Akehi, Yuko, Takashi, Yuichi, Koga, Daisuke, Shimokita, Eisuke, Tanihara, Fuminori, Kurahashi, Kiyoe, Yoshida, Sumiko, Mitsui, Yukari, Masuda, Shiho, Endo, Itsuro, Aihara, Ken‐ichi, Kagami, Shoji, Abe, Masahiro, Ferreri, Kevin, Fujitani, Yoshio, Matsuhisa, Munehide, Kuroda, Akio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248415/
https://www.ncbi.nlm.nih.gov/pubmed/35396829
http://dx.doi.org/10.1111/jdi.13806

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248415/
https://www.ncbi.nlm.nih.gov/pubmed/35396829
http://dx.doi.org/10.1111/jdi.13806

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