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Dabigatran and Wet AMD, Results From Retinal Pigment Epithelial Cell Monolayers, the Mouse Model of Choroidal Neovascularization, and Patients From the Medicare Data Base

BACKGROUND: Age-related macular degeneration (AMD), the leading cause of irreversible blindness in elderly Caucasian populations, includes destruction of the blood-retina barrier (BRB) generated by the retinal pigment epithelium-Bruch’s membrane complex (RPE/BrM), and complement activation. Thrombin...

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Detalles Bibliográficos
Autores principales: Akter, Tanjina, Annamalai, Balasubramaniam, Obert, Elisabeth, Simpson, Kit N., Rohrer, Bärbel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248746/
https://www.ncbi.nlm.nih.gov/pubmed/35784301
http://dx.doi.org/10.3389/fimmu.2022.896274