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Dabigatran and Wet AMD, Results From Retinal Pigment Epithelial Cell Monolayers, the Mouse Model of Choroidal Neovascularization, and Patients From the Medicare Data Base
BACKGROUND: Age-related macular degeneration (AMD), the leading cause of irreversible blindness in elderly Caucasian populations, includes destruction of the blood-retina barrier (BRB) generated by the retinal pigment epithelium-Bruch’s membrane complex (RPE/BrM), and complement activation. Thrombin...
Autores principales: | Akter, Tanjina, Annamalai, Balasubramaniam, Obert, Elisabeth, Simpson, Kit N., Rohrer, Bärbel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248746/ https://www.ncbi.nlm.nih.gov/pubmed/35784301 http://dx.doi.org/10.3389/fimmu.2022.896274 |
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