Inhibition of Heat Shock Protein B8 Alleviates Retinal Dysfunction and Ganglion Cells Loss Via Autophagy Suppression in Mouse Axonal Damage

PURPOSE: Heat shock protein B8 (HspB8) can be upregulated rapidly in many pathologic processes, but its role in traumatic optic neuropathy remains unclear. In this study, we investigated the involvement of autophagy in the effects of HspB8 by using the optic nerve crush (ONC) model. METHODS: Male C5...

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Detalles Bibliográficos
Autores principales: Xie, Feijia, Li, Zongyuan, Yang, Ning, Yang, Jiayi, Hua, Dihao, Luo, Jinyuan, He, Tao, Xing, Yiqiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2022
Materias:
Eye Movements, Strabismus, Amblyopia and Neuro-Ophthalmology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248752/
https://www.ncbi.nlm.nih.gov/pubmed/35758906
http://dx.doi.org/10.1167/iovs.63.6.28

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248752/
https://www.ncbi.nlm.nih.gov/pubmed/35758906
http://dx.doi.org/10.1167/iovs.63.6.28

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