TFEB-Mediated Lysosomal Restoration Alleviates High Glucose-Induced Cataracts Via Attenuating Oxidative Stress

PURPOSE: Diabetic cataract (DC) is a visual disorder arising from diabetes mellitus (DM). Autophagy, a prosurvival intracellular process through lysosomal fusion and degradation, has been implicated in multiple diabetic complications. Herein, we performed in vivo and in vitro assays to explore the s...

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Detalles Bibliográficos
Autores principales: Sun, Yan, Wang, Xiaoran, Chen, Baoxin, Huang, Mi, Ma, Pengjuan, Xiong, Lang, Huang, Jingqi, Chen, Jieping, Huang, Shan, Liu, Yizhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2022
Materias:
Lens
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248753/
https://www.ncbi.nlm.nih.gov/pubmed/35758908
http://dx.doi.org/10.1167/iovs.63.6.26

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248753/
https://www.ncbi.nlm.nih.gov/pubmed/35758908
http://dx.doi.org/10.1167/iovs.63.6.26

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