TFEB-Mediated Lysosomal Restoration Alleviates High Glucose-Induced Cataracts Via Attenuating Oxidative Stress

PURPOSE: Diabetic cataract (DC) is a visual disorder arising from diabetes mellitus (DM). Autophagy, a prosurvival intracellular process through lysosomal fusion and degradation, has been implicated in multiple diabetic complications. Herein, we performed in vivo and in vitro assays to explore the s...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Yan, Wang, Xiaoran, Chen, Baoxin, Huang, Mi, Ma, Pengjuan, Xiong, Lang, Huang, Jingqi, Chen, Jieping, Huang, Shan, Liu, Yizhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2022
Materias:
Lens
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248753/
https://www.ncbi.nlm.nih.gov/pubmed/35758908
http://dx.doi.org/10.1167/iovs.63.6.26

Ejemplares similares

Ejemplares similares