A trial design to maximize knowledge of the effects of rodatristat ethyl in the treatment of pulmonary arterial hypertension (ELEVATE 2)

Serotonin plays a key role in the development and maintenance of the pathobiology associated with pulmonary arterial hypertension (PAH). Platelet‐driven and locally produced serotonin from lung tissue and arterial endothelial cells induce excessive growth of pulmonary artery smooth muscle cells. The...

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Detalles Bibliográficos
Autores principales: Lazarus, Howard M., Denning, Jill, Wring, Stephen, Palacios, Michelle, Hoffman, Sidra, Crizer, Katelyn, Kamau‐Kelley, Watiri, Symonds, William, Feldman, Jeremy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248796/
https://www.ncbi.nlm.nih.gov/pubmed/35795492
http://dx.doi.org/10.1002/pul2.12088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248796/
https://www.ncbi.nlm.nih.gov/pubmed/35795492
http://dx.doi.org/10.1002/pul2.12088

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