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Disrupted Alpha-Ketoglutarate Homeostasis: Understanding Kidney Diseases from the View of Metabolism and Beyond

Alpha-ketoglutarate (AKG) is a key intermediate of various metabolic pathways including tricarboxylic acid (TCA) cycle, anabolic and catabolic reactions of amino acids, and collagen biosynthesis. Meanwhile, AKG also participates in multiple signaling pathways related to cellular redox regulation, ep...

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Detalles Bibliográficos
Autores principales: Guo, Lijing, Chen, Shihua, Ou, Liping, Li, Shangmei, Ye, Zhen-Nan, Liu, Hua-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248815/
https://www.ncbi.nlm.nih.gov/pubmed/35783031
http://dx.doi.org/10.2147/DMSO.S369090