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Disrupted Alpha-Ketoglutarate Homeostasis: Understanding Kidney Diseases from the View of Metabolism and Beyond
Alpha-ketoglutarate (AKG) is a key intermediate of various metabolic pathways including tricarboxylic acid (TCA) cycle, anabolic and catabolic reactions of amino acids, and collagen biosynthesis. Meanwhile, AKG also participates in multiple signaling pathways related to cellular redox regulation, ep...
Autores principales: | Guo, Lijing, Chen, Shihua, Ou, Liping, Li, Shangmei, Ye, Zhen-Nan, Liu, Hua-Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248815/ https://www.ncbi.nlm.nih.gov/pubmed/35783031 http://dx.doi.org/10.2147/DMSO.S369090 |
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