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High-resolution structure determination using high-throughput electron cryo-tomography

Tomographic reconstruction of frozen-hydrated specimens followed by extraction and averaging of sub-tomograms has successfully been used to determine the structure of macromolecules in their native environment at resolutions that are high enough to reveal molecular level interactions. The low throug...

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Detalles Bibliográficos
Autores principales: Liu, Hsuan-Fu, Zhou, Ye, Bartesaghi, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248845/
https://www.ncbi.nlm.nih.gov/pubmed/35775981
http://dx.doi.org/10.1107/S2059798322005010