Inflammatory adipose activates a nutritional immunity pathway leading to retinal dysfunction

Age-related macular degeneration (AMD), the leading cause of irreversible blindness among Americans over 50, is characterized by dysfunction and death of retinal pigment epithelial (RPE) cells. The RPE accumulates iron in AMD, and iron overload triggers RPE cell death in vitro and in vivo. However,...

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Detalles Bibliográficos
Autores principales: Sterling, Jacob K., Baumann, Bailey, Foshe, Sierra, Voigt, Andrew, Guttha, Samyuktha, Alnemri, Ahab, McCright, Sam J., Li, Mingyao, Zauhar, Randy J., Montezuma, Sandra R., Kapphahn, Rebecca J., Chavali, Venkata R.M., Hill, David A., Ferrington, Deborah A., Stambolian, Dwight, Mullins, Robert F., Merrick, David, Dunaief, Joshua L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248858/
https://www.ncbi.nlm.nih.gov/pubmed/35705048
http://dx.doi.org/10.1016/j.celrep.2022.110942

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248858/
https://www.ncbi.nlm.nih.gov/pubmed/35705048
http://dx.doi.org/10.1016/j.celrep.2022.110942

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