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Profiling the quantitative occupancy of myriad transcription factors across conditions by modeling chromatin accessibility data

Over a thousand different transcription factors (TFs) bind with varying occupancy across the human genome. Chromatin immunoprecipitation (ChIP) can assay occupancy genome-wide, but only one TF at a time, limiting our ability to comprehensively observe the TF occupancy landscape, let alone quantify h...

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Detalles Bibliográficos
Autores principales: Luo, Kaixuan, Zhong, Jianling, Safi, Alexias, Hong, Linda K., Tewari, Alok K., Song, Lingyun, Reddy, Timothy E., Ma, Li, Crawford, Gregory E., Hartemink, Alexander J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248881/
https://www.ncbi.nlm.nih.gov/pubmed/35609992
http://dx.doi.org/10.1101/gr.272203.120