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Profiling the quantitative occupancy of myriad transcription factors across conditions by modeling chromatin accessibility data
Over a thousand different transcription factors (TFs) bind with varying occupancy across the human genome. Chromatin immunoprecipitation (ChIP) can assay occupancy genome-wide, but only one TF at a time, limiting our ability to comprehensively observe the TF occupancy landscape, let alone quantify h...
Autores principales: | Luo, Kaixuan, Zhong, Jianling, Safi, Alexias, Hong, Linda K., Tewari, Alok K., Song, Lingyun, Reddy, Timothy E., Ma, Li, Crawford, Gregory E., Hartemink, Alexander J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248881/ https://www.ncbi.nlm.nih.gov/pubmed/35609992 http://dx.doi.org/10.1101/gr.272203.120 |
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