Cargando…

Towards Understanding the Relationship Between ER Stress and Unfolded Protein Response in Amyotrophic Lateral Sclerosis

Biological stress due to the aberrant buildup of misfolded/unfolded proteins in the endoplasmic reticulum (ER) is considered a key reason behind many human neurodegenerative diseases. Cells adapted to ER stress through the activation of an integrated signal transduction pathway known as the unfolded...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Chenxuan, Liao, Yong, Rahaman, Abdul, Kumar, Vijay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248913/
https://www.ncbi.nlm.nih.gov/pubmed/35783140
http://dx.doi.org/10.3389/fnagi.2022.892518