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Gastroprotective activity of (E)-ethyl-12-cyclohexyl-4,5-dihydroxydodec-2-enoate, a compound isolated from Heliotropium indicum: role of nitric oxide, prostaglandins, and sulfhydryls in its mechanism of action

CONTEXT: The gastroprotective effect of Heliotropium indicum L. (Boraginaceae), a plant traditionally used in Mexico to treat gastric ulcers, has been previously reported. However, no active compound was identified. OBJECTIVE: The current contribution aimed to isolate, through a bioassay-guided stud...

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Detalles Bibliográficos
Autores principales: López-Lorenzo, Yaraset, Sánchez-Mendoza, María Elena, Arrieta-Baez, Daniel, Perez-Ruiz, Adriana Guadalupe, Arrieta, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248942/
https://www.ncbi.nlm.nih.gov/pubmed/35764528
http://dx.doi.org/10.1080/13880209.2022.2087690