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Molecular Pharmacology of P2X Receptors: Exploring Druggable Domains Revealed by Structural Biology
Extracellular ATP is a critical signaling molecule that is found in a wide range of concentrations across cellular environments. The family of nonselective cation channels that sense extracellular ATP, termed P2X receptors (P2XRs), is composed of seven subtypes (P2X(1)-P2X(7)) that assemble as funct...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248971/ https://www.ncbi.nlm.nih.gov/pubmed/35784697 http://dx.doi.org/10.3389/fphar.2022.925880 |