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Molecular Pharmacology of P2X Receptors: Exploring Druggable Domains Revealed by Structural Biology

Extracellular ATP is a critical signaling molecule that is found in a wide range of concentrations across cellular environments. The family of nonselective cation channels that sense extracellular ATP, termed P2X receptors (P2XRs), is composed of seven subtypes (P2X(1)-P2X(7)) that assemble as funct...

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Detalles Bibliográficos
Autores principales:	Oken, Adam C., Krishnamurthy, Ipsita, Savage, Jonathan C., Lisi, Nicolas E., Godsey, Michael H., Mansoor, Steven E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248971/ https://www.ncbi.nlm.nih.gov/pubmed/35784697 http://dx.doi.org/10.3389/fphar.2022.925880

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