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Bio-Evaluation of (99m)Tc-Labeled Homodimeric Chalcone Derivative as Amyloid-β-Targeting Probe

Chalcone derivatives have been successfully utilized for a range of biological applications and can cross the blood–brain barrier easily. β-amyloid-specific bis-chalcone derivative, 6,9-bis(carboxymethyl)-14-(4-[(E)-3-(4-(dimethylamino)phenyl)acryloyl]phenoxy)-3-(2-[(2-(4-[(E)-3-(4-(dimethylamino)ph...

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Detalles Bibliográficos
Autores principales: Mann, Garima, Chauhan, Kanchan, Kumar, Vikas, Daksh, Shivani, Kumar, Nikhil, Thirumal, M., Datta, Anupama
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249127/
https://www.ncbi.nlm.nih.gov/pubmed/35783620
http://dx.doi.org/10.3389/fmed.2022.813465