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SCRaPL: A Bayesian hierarchical framework for detecting technical associates in single cell multiomics data

Single-cell multi-omics assays offer unprecedented opportunities to explore epigenetic regulation at cellular level. However, high levels of technical noise and data sparsity frequently lead to a lack of statistical power in correlative analyses, identifying very few, if any, significant association...

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Detalles Bibliográficos
Autores principales: Maniatis, Christos, Vallejos, Catalina A., Sanguinetti, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249169/
https://www.ncbi.nlm.nih.gov/pubmed/35727848
http://dx.doi.org/10.1371/journal.pcbi.1010163