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Integration of bioassay and non-target metabolite analysis of tomato reveals that β-carotene and lycopene activate the adiponectin signaling pathway, including AMPK phosphorylation

Adiponectin, an adipokine, regulates glucose metabolism and insulin sensitivity through the adiponectin receptor (AdipoR). In this study, we searched for metabolites that activate the adiponectin signaling pathway from tomato (Solanum lycopersicu). Metabolites of mature tomato were separated into 55...

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Detalles Bibliográficos
Autores principales: Mohri, Shinsuke, Takahashi, Haruya, Sakai, Maiko, Waki, Naoko, Takahashi, Shingo, Aizawa, Koichi, Suganuma, Hiroyuki, Ara, Takeshi, Sugawara, Tatsuya, Shibata, Daisuke, Matsumura, Yasuki, Goto, Tsuyoshi, Kawada, Teruo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249195/
https://www.ncbi.nlm.nih.gov/pubmed/35776737
http://dx.doi.org/10.1371/journal.pone.0267248