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Integration of bioassay and non-target metabolite analysis of tomato reveals that β-carotene and lycopene activate the adiponectin signaling pathway, including AMPK phosphorylation
Adiponectin, an adipokine, regulates glucose metabolism and insulin sensitivity through the adiponectin receptor (AdipoR). In this study, we searched for metabolites that activate the adiponectin signaling pathway from tomato (Solanum lycopersicu). Metabolites of mature tomato were separated into 55...
Autores principales: | Mohri, Shinsuke, Takahashi, Haruya, Sakai, Maiko, Waki, Naoko, Takahashi, Shingo, Aizawa, Koichi, Suganuma, Hiroyuki, Ara, Takeshi, Sugawara, Tatsuya, Shibata, Daisuke, Matsumura, Yasuki, Goto, Tsuyoshi, Kawada, Teruo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249195/ https://www.ncbi.nlm.nih.gov/pubmed/35776737 http://dx.doi.org/10.1371/journal.pone.0267248 |
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