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Vaccine with bacterium‐like particles displaying HIV‐1 gp120 trimer elicits specific mucosal responses and neutralizing antibodies in rhesus macaques

Preclinical studies have shown that the induction of secretory IgA (sIgA) in mucosa and neutralizing antibodies (NAbs) in sera is essential for designing vaccines that can effectively block the transmission of HIV‐1. We previously showed that a vaccine consisting of bacterium‐like particles (BLPs) d...

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Detalles Bibliográficos
Autores principales: Wang, Huaiyu, Li, Pingchao, Zhang, Mo, Bi, Jinpeng, He, Yizi, Li, Fangshen, Yu, Rongzhen, Gao, Feng, Kong, Wei, Yu, Bin, Chen, Ling, Yu, Xianghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249329/
https://www.ncbi.nlm.nih.gov/pubmed/35290714
http://dx.doi.org/10.1111/1751-7915.14022