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Vaccine with bacterium‐like particles displaying HIV‐1 gp120 trimer elicits specific mucosal responses and neutralizing antibodies in rhesus macaques
Preclinical studies have shown that the induction of secretory IgA (sIgA) in mucosa and neutralizing antibodies (NAbs) in sera is essential for designing vaccines that can effectively block the transmission of HIV‐1. We previously showed that a vaccine consisting of bacterium‐like particles (BLPs) d...
Autores principales: | Wang, Huaiyu, Li, Pingchao, Zhang, Mo, Bi, Jinpeng, He, Yizi, Li, Fangshen, Yu, Rongzhen, Gao, Feng, Kong, Wei, Yu, Bin, Chen, Ling, Yu, Xianghui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249329/ https://www.ncbi.nlm.nih.gov/pubmed/35290714 http://dx.doi.org/10.1111/1751-7915.14022 |
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