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Inhibition of GSDMD Activates Poly(ADP-ribosyl)ation and Promotes Myocardial Ischemia-Reperfusion Injury

The precise control of cardiomyocyte viability is imperative to combat myocardial ischemia-reperfusion injury (I/R), in which apoptosis and pyroptosis putatively contribute to the process. Recent researches indicated that GSDMD is involved in I/R as an executive protein of pyroptosis. However, its e...

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Detalles Bibliográficos
Autores principales: Zhang, Zheng-hao, Zhang, Zi-guan, Chen, Min-wei, Yang, Ying, Li, Run-jing, Xu, Jia-jia, Yang, Cui, Li, Yu-ying, Chen, Hong-wei, Liu, Shi-xiao, Li, Yan-ling, Luo, Ping, Liu, Yi-jiang, Chen, Wen-bo, Shan, Zhong-gui, Huang, Zheng-rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249530/
https://www.ncbi.nlm.nih.gov/pubmed/35783187
http://dx.doi.org/10.1155/2022/1115749