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Pre-existing chromatin accessibility of switchable repressive compartment delineates cell plasticity

Cell plasticity endows differentiated cells with competence to be reprogrammed to other lineages. Although extrinsic factors driving cell-identity conversion have been extensively characterized, it remains elusive which intrinsic epigenetic attributes, including high-order chromatin organization, de...

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Detalles Bibliográficos
Autores principales: Ma, Xiaolong, Cao, Xuan, Zhu, Linying, Li, Ying, Wang, Xuelong, Wu, Baihua, Wei, Gang, Hui, Lijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249582/
https://www.ncbi.nlm.nih.gov/pubmed/35795460
http://dx.doi.org/10.1093/nsr/nwab230