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KOMB: K-core based de novo characterization of copy number variation in microbiomes

Characterizing metagenomes via kmer-based, database-dependent taxonomic classification has yielded key insights into underlying microbiome dynamics. However, novel approaches are needed to track community dynamics and genomic flux within metagenomes, particularly in response to perturbations. We des...

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Detalles Bibliográficos
Autores principales: Balaji, Advait, Sapoval, Nicolae, Seto, Charlie, Leo Elworth, R.A., Fu, Yilei, Nute, Michael G., Savidge, Tor, Segarra, Santiago, Treangen, Todd J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249589/
https://www.ncbi.nlm.nih.gov/pubmed/35832621
http://dx.doi.org/10.1016/j.csbj.2022.06.019