The glucocorticoid receptor represses, whereas C/EBPβ can enhance or repress CYP26A1 transcription

Retinoic acid (RA) counters insulin’s metabolic actions. Insulin reduces liver RA biosynthesis by exporting FoxO1 from nuclei. RA induces its catabolism, catalyzed by CYP26A1. A CYP26A1 contribution to RA homeostasis with changes in energy status had not been investigated. We found that glucagon, co...

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Detalles Bibliográficos
Autores principales: Yoo, Hong Sik, Rodriguez, Adrienne, You, Dongjoo, Lee, Rebecca A., Cockrum, Michael A., Grimes, Jack A., Wang, Jen-Chywan, Kang, Sona, Napoli, Joseph L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249609/
https://www.ncbi.nlm.nih.gov/pubmed/35789854
http://dx.doi.org/10.1016/j.isci.2022.104564

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249609/
https://www.ncbi.nlm.nih.gov/pubmed/35789854
http://dx.doi.org/10.1016/j.isci.2022.104564

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